Nyob rau xyoo 1990, Swiss kws kho mob tau pom tias platelets tuaj yeem tsim ntau yam kev loj hlob ntawm qhov siab, uas tuaj yeem kho cov ntaub so ntswg sai thiab zoo.Tom qab ntawd, PRP tau siv ntau yam kev phais sab hauv thiab sab nraud, phais yas, hloov daim tawv nqaij, thiab lwm yam.
Peb yav dhau los qhia txog daim ntawv thov ntawm PRP (Platelets Rich Plasma) hauv kev hloov cov plaub hau los pab kho qhov txhab thiab cov plaub hau loj hlob;Tau kawg, qhov kev sim tom ntej sim yog txhawm rau txhim kho cov plaub hau thawj zaug los ntawm kev txhaj tshuaj PRP.Cia peb saib seb cov txiaj ntsig yuav ua tiav los ntawm kev txhaj tshuaj autologous platelet enriched plasma thiab ntau yam kev loj hlob rau cov txiv neej cov neeg mob alopecia, uas kuj yog ib txoj kev kho uas peb tuaj yeem xav siv los tawm tsam cov plaub hau.
Ua ntej thiab thaum tag nrho cov txheej txheem ntawm kev hloov cov plaub hau, cov neeg mob kho nrog PRP thiab cov tsis txhaj tshuaj PRP tuaj yeem ua rau cov plaub hau loj hlob sai.Nyob rau tib lub sijhawm, tus kws sau ntawv kuj tau tshaj tawm txoj kev tshawb fawb kom paub meej tias seb puas muaj platelet nplua nuj plasma muaj txiaj ntsig zoo ib yam rau kev txhim kho cov plaub hau zoo.Yuav siv lub qhov txhab zoo li cas thiab qhov loj hlob npaum li cas yuav tsum tau txhaj ncaj qha kom ua tau zoo?PRP puas tuaj yeem thim rov qab maj mam thinning ntawm cov plaub hau hauv androgenic alopecia, lossis nws puas tuaj yeem txhawb cov plaub hau kev loj hlob los txhim kho androgenic alopecia lossis lwm yam kab mob plaub hau?
Hauv yim lub hlis me me no, PRP tau txhaj rau hauv tawv taub hau ntawm androgenic alopecia thiab alopecia kawm.Piv nrog rau pawg tswj hwm, nws tuaj yeem thim rov qab maj mam thinning ntawm cov plaub hau;Tsis tas li ntawd, thaum txhaj rau hauv cov neeg mob uas muaj qhov tawv taub hau, cov plaub hau tshiab tuaj yeem pom ib hlis tom qab, thiab cov nyhuv tuaj yeem kav ntev tshaj li yim lub hlis.
Taw qhia
Xyoo 2004, thaum ib tus kws tshawb fawb tau kho tus nees lub qhov txhab nrog PRP, lub qhov txhab kho nyob rau hauv ib lub hlis thiab cov plaub hau loj hlob, thiab tom qab ntawd PRP tau siv rau kev phais plaub hau;Cov kws tshawb fawb kuj tau sim txhaj tshuaj PRP ntawm cov tawv taub hau ntawm qee cov neeg mob ua ntej kev hloov cov plaub hau, thiab pom tias cov plaub hau ntawm cov neeg mob zoo li thicker (1).Cov kws tshawb fawb ntseeg tias revascularization thiab cov txiaj ntsig ntawm cov ntsiab lus siab ntawm kev loj hlob tuaj yeem txhawb kev loj hlob ntawm cov plaub hau follicle hlwb hauv tawv taub hau ntawm thaj chaw tsis ua haujlwm.Cov ntshav tshwj xeeb ua tiav.Platelets raug cais los ntawm lwm cov plasma proteins thiab muaj cov platelets siab.Txhawm rau kom ncav cuag tus qauv ntawm cov txiaj ntsig kho mob, los ntawm 1 microliter (0.000001 liter) muaj 150000-450000 platelets mus rau 1 microliter (0.000001 liter) muaj 1000000 platelets (2).
Platelet α muaj xya yam kev loj hlob hauv cov granules, suav nrog kev loj hlob ntawm epithelial, fibroblast kev loj hlob zoo, thrombogen kev loj hlob zoo thiab hloov pauv kev loj hlob β, transforming kev loj hlob factor α, Interleukin-1, thiab vascular endothelial kev loj hlob yam (VEGF).Tsis tas li ntawd, cov tshuaj tua kab mob peptides, catecholamines, serotonin, Osteonectin, von Willebrand factor, proaccelenn thiab lwm yam tshuaj ntxiv.Cov khoom tuab muaj ntau tshaj 100 hom kev loj hlob, uas tuaj yeem ua rau qhov txhab.Ntxiv nrog rau qhov kev loj hlob, cov kab mob sib cais platelet sparse plasma (PPP) muaj peb lub xov tooj ntawm tes adhesion molecules (CAM), Fibrin, fibronectin, thiab vitronectin, cov protein ntau uas teeb tsa cov qauv tseem ceeb thiab cov ceg los tswj kev loj hlob ntawm tes, adhesion, proliferation, kev sib txawv thiab kev tsim kho tshiab.
Takakura, et al.thov tias PDCF (platelet derived kev loj hlob yam tseem ceeb) teeb liab muaj feem xyuam rau kev cuam tshuam ntawm epidermal plaub hau follicles thiab dermal stromal hlwb, thiab tsim nyog rau kev tsim cov plaub hau ducts (3).Xyoo 2001, Yano et al.taw qhia tias VFLGF feem ntau tswj lub voj voog ntawm cov plaub hau follicle, muab cov pov thawj ncaj qha tias ua kom cov plaub hau follicle vascular reconstruction tuaj yeem txhawb cov plaub hau kev loj hlob thiab nce cov plaub hau follicle thiab plaub hau loj (4).
PS: Platelet muab tau qhov kev loj hlob, PDCF.Thawj qhov kev loj hlob tau pom zoo los ntawm US FDA los kho mob ntawm daim tawv nqaij raug mob yog thawj qhov kev loj hlob tawm los ntawm stimulation tom qab raug mob ntawm daim tawv nqaij.
PS: Vascular endothelial kev loj hlob yam, VEGF.Nws yog ib qho tseem ceeb tshaj plaws ntawm kev tswj hwm kev tswj hwm endothelial cell proliferation, angiogenesis, vasculogenesis thiab vascular permeability.
Yog tias peb ntseeg tias thaum cov hauv paus plaub hau tau poob mus rau qhov uas peb tsis tuaj yeem pom cov plaub hau loj hlob ntawm qhov muag liab qab, tseem muaj lub caij nyoog rau cov hauv paus plaub hau kom loj hlob plaub hau (5).Tsis tas li ntawd, yog cov hauv paus plaub hau ntawm cov plaub hau zoo tib yam li cov plaub hau ntxhib, muaj cov qia hlwb txaus nyob rau hauv cov kab mob epidermis thiab bulge (6), nws muaj peev xwm ua rau cov plaub hau thinner thiab thicker nyob rau hauv txiv neej baldness.
Post lub sij hawm: Dec-20-2022